PRT062607 Hydrochloride hydrofolate Smiles: CN1[C@@H]2C[C@H](C[C@H]1CC2)OC(C1C=CC=CC=1)C1C=CC=CC=1

Smiles: CN1[C@@H]2C[C@H](C[C@H]1CC2)OC(C1C=CC=CC=1)C1C=CC=CC=1

InChiKey: ABSXPNGWJFAPRT-UHFFFAOYSA-N

a protein implicated in DNA damage repair and apoptosis

GSK2334470 will be a useful tool for delineating the roles of PDK1 in biological processes

PRT062607 Hydrochloride hydrofolate Smiles: CN1[C@@H]2C[C@H](C[C@H]1CC2)OC(C1C=CC=CC=1)C1C=CC=CC=1PRT062607, also known as P505 15, PRT2607, PRT62607, and BIIB057, is a novel, highly selective, and orally bioavailable small molecule SYK inhibitor (SYK IC(50) = 1 nM) with anti SYK activity that is at least 80 fold greater than its affinity for other kinases. P505 15 successfully inhibited SYK mediated B cell receptor signaling and decreased cell viability in NHL and CLL. Product information CAS Number: 1370261 97 4 Molecular Weight: 429. 91