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7(2):182-5
Testing of INCB024360-analog in mice demonstrated pharmacodynamic inhibition of IDO
17-dien-8-yl]-2-oxoethyl acetate
4-tetrahydropyrimidin-1-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate
PROTAC MDM2 Degrader-2 statin D6 Sodium 7(2):182-5PROTAC MDM2 Degrader 2 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader 2 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase. Product information CAS Number: 2249944 99 6 Molecular Weight: 1391. 22 Formula: C70H76Cl4N10O12 Chemical Name: 2 {4 [(4R,5S) 4,5 bis(4 chlorophenyl) 2 [4 methoxy 2 (propan 2 yloxy)phenyl] 4,5 dihydro 1H imidazole 1 carbonyl] 2 oxopiperazin 1 yl} N (2 {2 [2 (2 {4 [(4R,5S)