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NPS 2143 blocks increases in cytoplasmic Ca2+ concentrations with IC50 of 43 nM elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor
EB-47 Catalog No.:M19047-C NPS 2143 blocks increases inEB 47, a potent and selective PARP 1 ARTD 1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM. EB 47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite. Product information CAS Number: 366454 36 6 Molecular Weight: 537. 53 Formula: C24H27N9O6 Chemical Name: 2 {4 [(2S, 3S, 4R, 5R) 5 (6 amino 9H purin 9 yl) 3, 4 dihydroxyoxolane 2 carbonyl]piperazin 1 yl} N (1 oxo 2,
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