IC-87114 licin InChi: InChI=1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/h3-7

InChi: InChI=1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/h3-7

Nepafenac also blunts the increase in VEGF mRNA in the retina induced by ischemia

a potent and specific inhibitor of the tyrosine kinase activity of receptors for the EGF family of growth factors

Knutson SK

IC-87114 licin InChi: InChI=1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/h3-7IC 87114 is a potent and ATP competitive PI3K p110 isoform selective inhibitor (IC50 = 60 nM). It Inhibits p110, p110 and p110 only at much higher concentrations. It does not inhibit other PIK related kinases such as ATM, ATR, DNA PK, and mTOR even at concentrations up to 100 M. Product information CAS Number: 371242 69 2 Molecular Weight: 397. 43 Formula: C22H19N7O Synonym: IC87114 IC 87114 Chemical Name: 2 ((6 amino 9H purin 9 yl)methyl) 5 methyl 3