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The mechanism is that apogossypolone binds to Bcl-2 and prevents its association with BH3-only pro-apoptotic proteins
giving an intestinal loop weight/length ratio similar to that in PBS-injected loops
Cortexolone 17α-propionate
Formula: C10H14N5Na2O14P3
ALK-IN-13 27010 The mechanism is that apogossypoloneProduct information CAS Number: 1197953 88 0 Molecular Weight: 584. 09 Formula: C29H39ClN7O2P Chemical Name: 5 chloro N4 [4 (dimethylphosphoryl)phenyl] N2 {2 methoxy 4 [4 (4 methylpiperazin 1 yl)piperidin 1 yl]phenyl}pyrimidine 2, 4 diamine Smiles: CN1CCN(CC1)C1CCN(CC1)C1=CC(OC)=C(C=C1)NC1=NC(NC2C=CC(=CC=2)P(C)(C)=O)=C(Cl)C=N1 InChiKey: OAYGRXFKOOCTTP UHFFFAOYSA N InChi: InChI=1S C29H39ClN7O2P c1 35 15 17 37(18 16 35)22 11 13 36(14 12 22)23 7 10
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