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Use efficient removal I feel bad saying something so obvious, but in a metagame dominated by Decay and Lilly, as well as decks that don't want to interact at all, Infect has a huge edge

It's incredibly limited - it can only recur a small number of targets, and often is just an overcosted 6/6 with nothing else save vigilance

GX Strike of Neos breaks through the old power barrier with cards never before imagined The first Level 4 monster with an unconditional 2000 attack points The first Level 6 monster with an unconditional 2600 attack points Ritual Monsters and Normal Monsters become better than ever with new support cards Introducing a new clan of Samurai Warriors, a whole new, competitive Deck type.

This means that the player can summon the card only in sync with another monster