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17(8):2502-11
The combination of XL765 (30 mg/kg) with chloroquine (50 mg/kg) results in significant inhibition of BxPC-3 xenograft growth in mice models
Smiles: COCC1(CO)C(=O)C2CCN1CC2
InChi: InChI=1S/C18H15FN4O/c1-22-9-14(8-21-22)12-4-5-13(16(19)7-12)10-23-11-17-15(18(23)24)3-2-6-20-17/h2-9H
MDL 72832 hydrochloride Catalog No.:M22802-C 17(8):2502-11MDL 72832 hydrochloride is a potent and selective ligand for 5 HT1A receptor with pIC50 value of 9. 1 . The 5 HT1A receptor is a G protein coupled receptor for endogenous neurotransmitter serotonin (5 HT) and mediates inhibitory neurotransmission. MDL 72832 hydrochloride is a potent and selective ligand for 5 HT1A receptor . Also, MDL 72832 exhibited affinity with pKD values of 6. 32 and 6. 34 for 5 HT1C and 5 HT1D receptors, respectively . In rats,