UK-157147 Catalog No.:M29600-C in the absence or presence

in the absence or presence of the unlabelled p53 consensus oligonucleotide) restores p53-specific DNA binding activity to p53R273H (a DNA contact mutant) and p53R175H (a structural mutant) in WiDr colon tumour cells harbouring p53R273H and KLE cells with p53R175H

Vp-TSL targets specifically aortic plaque endothelial VCAM-1 and CCR2 antagonist 4 hydrochloride reduces the mouse monocyte/macrophage cell line (RAW 264

50% at 50 mg/kg/d and 96% at 100 mg/kg/d) with numerous partial regressions (>50% reduction from baseline size) at the higher dose level in 9/12 animals

3)17/h11-13

UK-157147 Catalog No.:M29600-C in the absence or presenceUK 157147 is a substrate for UDP glucuronosyltransferases (UGT1A1) with a Km value of 105 M. Product information CAS Number: 162704 20 3 Molecular Weight: 472. 51 Formula: C23H24N2O7S Chemical Name: 6 {[(3S,4R) 3 hydroxy 6 (3 hydroxybenzenesulfonyl) 2,2,3 trimethyl 3,4 dihydro 2H 1 benzopyran 4 yl]oxy} 2 methyl 2,3 dihydropyridazin 3 one Smiles: CC1(C)OC2=CC=C(C=C2[C@@H](OC2C=CC(=O)N(C)N=2)[C@]1(C)O)S(=O)(=O)C1=CC=CC(O)=C1 InChiKey: MOZBVDKKWDXRGH