Vinyl-L-NIO (hydrochloride) Catalog No.:M22281-C 4-dichlorophenyl)methyl]morpholin-2-yl]methyl}carbamoyl)amino]methyl}benzamide

4-dichlorophenyl)methyl]morpholin-2-yl]methyl}carbamoyl)amino]methyl}benzamide

m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs

binds to BRS-3 with high affinity (mouse Ki = 1

PKCß inhibitor

Vinyl-L-NIO (hydrochloride) Catalog No.:M22281-C 4-dichlorophenyl)methyl]morpholin-2-yl]methyl}carbamoyl)amino]methyl}benzamideIC50: 100 nM, 12 and 60 M for nNOS, eNOS, and iNOS, respectively Vinyl L NIO is a potent and selective inhibitor of nNOS. Nitric oxide synthase (NOS) catalyzes the NADPH and O2 dependent conversion of L arginine to nitric oxide (NO) and citrulline. Three isoforms including the neuronal (nNOS), endothelial, and inducible have currently been identified. Since NO overproduction is able to contribute to various pathophysiological conditions, NOS