Asenapine Hydrochloride - CAS# 1412458-61-7 uorowillardiine hydrochloride BSJ-03-123 is a phthalimide-based degrader

BSJ-03-123 is a phthalimide-based degrader that exploits protein-interface determinants to achieve proteome-wide selectivity for the degradation of cyclin-dependent kinase 6 (CDK6)

PubMed PMID: 31757294

Specificity of polyclonal antibodies raised against a novel 24

2013 Oct 22

Asenapine Hydrochloride - CAS# 1412458-61-7 uorowillardiine hydrochloride BSJ-03-123 is a phthalimide-based degraderAsenapine, also known as Org 5222 and HSDB 8061, shows high affinity (pKi) for numerous receptors, including the serotonin 5 HT1A (8. 6), 5 HT1B (8. 4), 5 HT2A (10. 2), 5 HT2B (9. 8), 5 HT2C (10. 5), 5 HT5A (8. 8), 5 HT6 (9. 5), and 5 HT7 (9. 9) receptors, the adrenergic 1 (8. 9), 2A (8. 9), 2B (9. 5), and 2C (8. 9) receptors, the dopamine D1 (8. 9), D2 (8. 9), D3 (9. 4), and D4 (9. 0) receptors, and the histamine H1 (9. 0) and H2 (8. 2) receptors.