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interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2)
11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33/h4-6
L 735524 sulfate
Male Sprague-Dawley rats are dosed with the same IV (1 mg/kg) and PO (5
PF-3644022 Catalog No.:M12254-2 interacts with a cancer-associated proteinPF 3644022 is a potent, selective, orally active and ATP competitive MAPKAPK2 (MK2) inhibitor with an IC50 of 5. 2 nM and a Ki of 3 nM. PF 3644022 also inhibits MK3 and p38 regulated activated kinase (PRAK) with IC50s of 53 nM and 5. 0 nM, respectively. PF 3644022 potently inhibits TNF production and has anti inflammatory effect. Product information CAS Number: 1276121 88 0 Molecular Weight: 374. 46 Formula: C21H18N4OS Chemical Name: (15R) 15 methyl 5
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