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NVP-BEZ235 and NVP-BGT226
is a dual antagonist of the A2aR and A2bR adenosine receptors
InChiKey: GRRNUXAQVGOGFE-HUCHGKBZSA-N
InChiKey: LAZPBGZRMVRFKY-HNCPQSOCSA-N
Emricasan Catalog No.:M10978-10 NVP-BEZ235 and NVP-BGT226Emricasan, also known as IDN 6556 and PF 03491390, is a first in class caspase inhibitor in clinical trials for the treatment of liver diseases. Emricasan (IDN 6556) decreases liver injury and fibrosis in a murine model of non alcoholic steatohepatitis. IDN6556 facilitates marginal mass islet engraftment in a porcine islet autotransplant model. Oral IDN 6556 may lower aminotransferase activity in patients with chronic hepatitis C. Orally administered
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