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KZR-504 1739 InChi: InChI=1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H

SKU: 86702053700

4.1
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Description

InChi: InChI=1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H

InChiKey: AZUQEHCMDUSRLH-UHFFFAOYSA-N

but not by ROCK1 or ROCK2

shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A(2) through molecular docking

KZR-504 1739 InChi: InChI=1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3HKZR 504 is a highly selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2), with IC50s of 51 nM, 4. 274 M for LMP2 and LMP7, respectively. KZR 504 is of interest for the treatment of autoimmune disease. Product information CAS Number: 1629052 78 3 Molecular Weight: 413. 42 Formula: C21H23N3O6 Chemical Name: (2S) 3 hydroxy N [(2S) 1 [(2R) 2 methyloxiran 2 yl] 1 oxo 3 phenylpropan 2 yl] 2 [(6 oxo 1,6 dihydropyridin 2

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