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The IC50 values of Neocarzinostatin (72 hours) to C6 cells and U87MG cells were 493
InChiKey: JZAFPDYXTYKEQB-UHFFFAOYSA-N
5 of 5 C/L858R mice displays nearly 80% reduction in tumor volume by magnetic resonance imaging MRI after therapy with AZD-9291
ACT 078573 hydrochloride
OSU-T315 - CAS# 2070015-22-2 Size:10mg solid The IC50 values of NeocarzinostatinOSU T315 (ILK IN 1) is a small Integrin linked kinase (ILK) inhibitor with an IC50 of 0. 6 M, inhibiting PI3K AKT signaling by dephosphorylation of AKT Ser473 and other ILK targets (GSK 3 and myosin light chain). OSU T315 abrogates AKT activation by impeding AKT localization in lipid rafts and triggers caspase dependent apoptosis in an ILK independent manner[2]. OSU T315 causes cell death through apoptosis and autophagy. Product information CAS
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