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actin polymerization levels are significantly lower compared to controls (DMSO)
Lenalidomide and pomalidomide inhibits autoubiquitination of CRBN in HEK293 T cells expressing thalidomide-binding competent wild-type CRBN
54(6):352-8
3500 pmol/g)
Z-VAD(OMe)-FMK 539 HCl actin polymerization levels are significantlyZ VAD FMK is a cell permeable, irreversible pan caspase inhibitor. Z VAD FMK inhibits caspase processing and apoptosis induction in tumor cells in vitro (IC50 = 0. 0015 5. 8 mM). Z VAD(OMe) FMK is an ubiquitin carboxy terminal hydrolase L1 (UCHL1) inhibitor. Z VAD(OMe) FMK irreversibly modifies UCHL1 by targeting the active site of UCHL1. Product information CAS Number: 187389 52 2 Molecular Weight: 467. 49 Formula: C22H30FN3O7 Synonym: Z VAD(OMe) FMK
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