5, 15-DPP Size:Contact [email protected] for quotation CAS Number: 477-30-5

CAS Number: 477-30-5

26)14-9-11-17-16(18(22)15-19(17)23)10-7-5-6-8-12-20(24)25/h9

24 hours) decreases the viability of HeLa cervical cancer cells (IC50=15 µM)

InChi: InChI=1S/C10H16N2O5S/c13-8(14)4-2-1-3-7-9-6(5-18(7

5, 15-DPP Size:Contact [email protected] for quotation CAS Number: 477-30-55,15 diphenylporphyrin (5,15 DPP) is a selective STAT3 SH2 antagonist . Stat3 is constitutively activated in many human cancers. Stat3 functions as a critical mediator of oncogenic signaling through transcriptional activation of genes encoding apoptosis inhibitors, cell cycle regulators and inducers of angiogenesis . Aberrant STAT3 activity has been associated with transforming mechanisms induced by oncogenic tyrosine kinases . In vitro: 5,15 DPP