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with anti-diabetes and anti-diabetic nephropathy activity
is a first-in-class
chronic pain
InChiKey: JWBOIMRXGHLCPP-UHFFFAOYSA-N
Nav1.7-IN-8 opressin(rat) with anti-diabetes and anti-diabetic nephropathyNav1. 7 IN 8 is a potent blockage of NaV1. 7 with high selectivity for the inhibition of NaV1. 7 over the subtypes hNaV1. 1 and hNaV1. 5. Nav1. 7 IN 8 inhibits CYP2C9 and CYP3A4 with an IC50 of 0. 17 M and 0. 077 M, respectively. Nav1. 7 IN 8 displays significant analgesic effects in rodent models of acute and inflammatory pain. Product information CAS Number: 1432913 44 4 Molecular Weight: 535. 93 Formula: C21H12ClF2N5O4S2 Chemical Name: 4 [2 (3
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