RSM-932A hylisochamaejasmin 26'-tetracyclo[22

26'-tetracyclo[22

with the retinoic acid receptor gamma thought to be required for alveolar formation

Formula: C28H36O7

inhibits farnesylation of Ras

RSM-932A hylisochamaejasmin 26'-tetracyclo[22RSM 932A, also known as TCD 717, is a ChoK inhibitor, which targets the human choline kinase alpha, an enzyme involved in increased lipid metabolism of cancer cells. RSM 932A appears to have an altogether novel mechanism of inhibition and is synergistic with respect to both choline and ATP. RSM 932A have in vitro inhibitory activity in the low nanomolar range. RSM 932A significantly reduced parasitemia and induced the accumulation of trophozoites and