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Woska JR Jr
This agent has little or no affinity for serotonin type 3 (5-HT3)
ClH/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35
11-trihydroxy-1-methoxy-5
CHIR-98014 - CAS# 252935-94-7 Size:Solid 2 mg Woska JR JrCHIR98014, also known as CT 98024, is a reversible, cell permeable inhibitor of GSK3 and GSK3 (IC50 = 0. 65 and 0. 58 nM, respectively). It is inactive against a series of other serine threonine or tyrosine kinases. Through its effects on GSK3, CHIR98014 stimulates glycogen synthase in cells (EC50 = 106 nM), potentiates insulin dependent glucose transport in isolated muscle strips, and improves glucose disposal in diabetic animals. CHIR98014 also
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