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14-hexaen-4-ol
Mcl1-IN-8 (Comp8) exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells
CAS Number: 1392487-51-2
1-4H3/b11-5-/t16-/m0/s1
RORγt Inverse agonist 8 gonist P550 (mouse rat) 14-hexaen-4-olRORt Inverse agonist 8 is a potent, selective, orally bioavailable RORt inverse agonist, with an IC50 of 19 nM for human RORt LBD. Product information CAS Number: 2079892 79 6 Molecular Weight: 475. 59 Formula: C26H33N7O2 Chemical Name: N (8 {[(3S) 4 cyclopentanecarbonyl 3 methylpiperazin 1 yl]methyl} 7 methylimidazo[1,2 a]pyridin 6 yl) 2 methylpyrimidine 5 carboxamide Smiles: C[C@H]1CN(CC2C3=NC=CN3C=C(NC(=O)C3=CN=C(C)N=C3)C=2C)CCN1C(=O)C1CCCC1
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