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PubMed PMID: 28208209
4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S
Gouni-Berthold I
6-dimorpholino-1
SC-514 - CAS# 354812-17-2 Catalog No.:M6663-2 PubMed PMID: 28208209SC 514, CAS No. 354812 17 2, is a selective and reversible inhibitor of IB kinase 2 (IKK2) that may target osteoclastogenesis. SC 514 dose dependently inhibits RANKL induced osteoclastogenesis and induced apoptosis and caspase 3 activation in RAW264. 7 cells. Targeting IKK by SC 514 may be a potential treatment for osteoclast related disorders such as osteoporosis and cancer induced bone loss. Product information CAS Number: 354812 17 2 Molecular