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CAS Number: 212141-54-3
Smiles: CN(C)CC[C@H](CSC1C=CC=CC=1)NC1=CC=C(C=C1[N+]([O-])=O)S(=O)(=O)NC(=O)C1C=CC(=CC=1)N1CCN(CC1)CC1=CC=CC=C1C1C=CC(Cl)=CC=1
5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide hydrate hydrochloride
triggering rapid accumulation of polyubiquitinated proteins
Pimelic Diphenylamide 106 nogin CAS Number: 212141-54-3Pimelic Diphenylamide 106 is a slow, tight binding inhibitor of class I HDAC (HDAC 1, 2, and 3, with IC50 values of 150 nM , 760nM, and 370 nM, respectively), demonstrating no activity against class II HDACs. IC50 value: 150 nM (HDAC1), 370 nM (HDAC3), 760nM(HDAC2)Target: HDAC in vitro: Pimelic Diphenylamide 106 has preference toward HDAC3 with Ki of 14 nM, 15 times lower than the Ki for HDAC1. Pimelic Diphenylamide 106 exhibits weaker inhibitory
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