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In mice bearing KARPAS-422 xenografts
Formula: C30H24N4O8
the doublet erlotinib and TAS-115 successfully inhibit PC-9/HGF tumor growth and delay tumor regrowth associated with sustained tumor vasculature inhibition even after cessation of the treatment
2011 Apr 29
D-3263 Catalog No.:M18774-C In mice bearing KARPAS-422 xenograftsD 3263 is an agonist of transient receptor potential melastatin member 8 (TRPM8) with potential antineoplastic activity. Product information CAS Number: 947257 66 1 Molecular Weight: 373. 49 Formula: C21H31N3O3 Chemical Name: 3 (2 aminoethyl) 5 methoxy 1 [(1R,2S,5R) 5 methyl 2 (propan 2 yl)cyclohexanecarbonyl] 2,3 dihydro 1H 1,3 benzodiazol 2 one Smiles: CC(C)[C@@H]1CC[C@@H](C)C[C@H]1C(=O)N1C2=CC=C(C=C2N(CCN)C1=O)OC InChiKey: ZGTYTFYRCIRWBL HYVNUMGLSA