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GC 14 3782 Tissue distribution of BLU-554 (10

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Description

Tissue distribution of BLU-554 (10 mg/kg

UCHL5 and USP14

14bR)-9-(acetyloxy)-8-hydroxy-4

Chemical Name: 1-(2-hydroxy-2-methylpropyl)-N-{5-[(7-methoxyquinolin-4-yl)oxy]pyridin-2-yl}-5-methyl-3-oxo-2-phenyl-2

GC 14 3782 Tissue distribution of BLU-554 (10GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 35 nM and 200 nM for hTR and hTR, respectively. Product information CAS Number: 447415 34 1 Molecular Weight: 449. 50 Formula: C26H27NO6 Chemical Name: 2 (4 {[6 hydroxy 4' nitro 5 (propan 2 yl) [1,1' biphenyl] 3 yl]methyl} 3,5 dimethylphenoxy)acetic acid Smiles: CC1C=C(C=C(C)C=1CC1C=C(C(C)C)C(O)=C(C=1)C1C=CC(=CC=1)[N+]([O ])=O)OCC(O)=O InChiKey: PBZAEAFSLYJVGD UHFFFAOYSA N

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