UM171 - Human HSC Self-renewal Agonist. size:Contact [email protected] for more infomation InChi: InChI=1S/C17H14N4O3S/c1-22-11-8-6-10(7-9-11)15-20-21-16(24-15)19-17-18-14-12(23-2)4-3-5-13(14)25-17/h3-9H

InChi: InChI=1S/C17H14N4O3S/c1-22-11-8-6-10(7-9-11)15-20-21-16(24-15)19-17-18-14-12(23-2)4-3-5-13(14)25-17/h3-9H

Formula: C22H37NO7

4-oxadiazol-5-yl]methoxy}piperidine-1-carboxylate

The present results suggest that a release of thyroid hormone might participate in the hyperthermic action of Protirelin

UM171 - Human HSC Self-renewal Agonist. size:Contact [email protected] for more infomation InChi: InChI=1S/C17H14N4O3S/c1-22-11-8-6-10(7-9-11)15-20-21-16(24-15)19-17-18-14-12(23-2)4-3-5-13(14)25-17/h3-9HUM171, CAS No. 1448724 09 1, is a potent small molecule that stimulates the ex vivo expansion of human hematopoietic stem cells HSC capable of reconstituting human hematopoiesis for at least 6 months in immunocompromised mice. It attenuates cell differentiation and promotes ex vivo expansion of long term human HSC (LT HSC) at 35 nM in 11 days fed batch cultures. UM171s mechanism is independent of suppression of the aryl hydrocarbon receptor (AHR) like