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CCG-63802 - CAS# 620112-78-9 Catalog No.:M10963-2 InChi: InChI=1S/C31H29F2N5O3

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Description

InChi: InChI=1S/C31H29F2N5O3

and Mannhemia

169939-93-9

11-dioxo-1

CCG-63802 - CAS# 620112-78-9 Catalog No.:M10963-2 InChi: InChI=1S/C31H29F2N5O3CCG 63802 is a potent and reversible inhibitor of RGS protein. CCG 63802 inhibits the interaction between RGS4 and Galpha(o) with an IC(50) value in the low micromolar range. CCG 63802 shows selectivity among RGS proteins with a potency order of RGS 4 > 19 = 16 > 8 >> 7. CCG 63802 inhibits the GTPase accelerating protein activity of RGS4, and thermal stability studies demonstrate binding to the RGS but not to Galpha(o). CCG 63802 represents a useful

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