Nabumetone Catalog No.:M8907-2 InChi: InChI=1S/C16H18N4O4

InChi: InChI=1S/C16H18N4O4

InChi: InChI=1S/C22H25N3O3/c26-14-13-25(12-11-19-15-23-21-4-2-1-3-20(19)21)16-18-7-5-17(6-8-18)9-10-22(27)24-28/h1-10

Disruption of Autophagic Degradation with ROC-325 Antagonizes Renal Cell Carcinoma Pathogenesis

Epub 2011 Apr 27

Nabumetone Catalog No.:M8907-2 InChi: InChI=1S/C16H18N4O4Nabumetone is a non steroidal anti inflammatory drug (NSAID), the only 1 naphthaleneacetic acid derivative. It is a nonacidic NSAID that is rapidly metabolized in the liver to a major active metabolite, 6 methoxy 2 naphthyl acetic acid. As found with previous NSAIDs, nabumetone's active metabolite inhibits the cyclooxygenase enzyme and preferentially blocks COX 2 activity (which is indirectly responsible for the production of inflammation and pain