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GNE-0946 Catalog No.:M21139-C InChiKey: FDGQSTZJBFJUBT-UHFFFAOYSA-N

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Description

InChiKey: FDGQSTZJBFJUBT-UHFFFAOYSA-N

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology

in human liver microsomes

and 10 μM) reduces STAT5 phosphorylation at concentrations that parallel the concentrations required to inhibit cell proliferation

GNE-0946 Catalog No.:M21139-C InChiKey: FDGQSTZJBFJUBT-UHFFFAOYSA-NGNE 0946 is a potent and selective ROR( RORc) agonist with an EC50 value of 4 nM for HEK 293 cell. Product information CAS Number: 1677667 24 1 Molecular Weight: 460. 79 Formula: C22H12ClF3N2O4 Chemical Name: 4 {3 [2 chloro 6 (trifluoromethyl)benzoyl]imidazo[1,5 a]pyridin 1 yl} 2 hydroxybenzoic acid Smiles: OC(=O)C1=CC=C(C=C1O)C1N=C(C(=O)C2C(Cl)=CC=CC=2C(F)(F)F)N2C=CC=CC2=1 InChiKey: UAAUZNSONHHQQI UHFFFAOYSA N InChi: InChI=1S C22H12ClF3N2O4 c23 14 5

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