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and shows selective for TLR8 over TLR7 (IC50=>50 µM)
VU0652925 is a PAR4 antagonist
surpassing the affinity of wild-type doubly-phosphorylated peptide
also known as SBE-beta-CD and Sulfobutylether beta-cyclodextrin
m-PEG4-amino-Mal Catalog No.:M32574-C and shows selective for TLR8m PEG4 amino Mal is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 1263044 81 0 Molecular Weight: 358. 39 Formula: C16H26N2O7 Chemical Name: 3 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl) N (2,5,8,11 tetraoxatridecan 13 yl)propanamide Smiles: COCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O InChiKey: DOHTYEHHGXSUJO UHFFFAOYSA N InChi: InChI=1S C16H26N2O7 c1 22 8 9 24 12 13 25 11 10 23 7 5 17 14(19)4 6 18 15(20)2 3
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