MMAF Hydrochloride 60031 Smiles: CN1CCN(CC1)C1C=CC(=CC=1)C(=O)NC1=NNC2CN(CC=21)C(=O)[C@H](OC)C1C=CC=CC=1

Smiles: CN1CCN(CC1)C1C=CC(=CC=1)C(=O)NC1=NNC2CN(CC=21)C(=O)[C@H](OC)C1C=CC=CC=1

Solubility: DMSO : 8

Administration of Pilaralisib (XL147) causes a dose-dependent decrease in phosphorylation of AKT

has been shown to reduce portal venous pressure in cirrhotic rats

MMAF Hydrochloride 60031 Smiles: CN1CCN(CC1)C1C=CC(=CC=1)C(=O)NC1=NNC2CN(CC=21)C(=O)[C@H](OC)C1C=CC=CC=1MMAF (Monomethylauristatin F) hydrochloride is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF hydrochloride is widely used as a cytotoxic component of antibody drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN CD19A. Product information CAS Number: 1415246 68 2 Molecular Weight: 768. 42 Formula: C39H66ClN5O8 Synonym: Monomethylauristatin F Hydrochloride Chemical Name: (2S) 2 [(2R) 2 [(R) [(2S) 1