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98(6):630-8
Smiles: CCOC1=CC(N)=C(Cl)C=C1C(=O)NCC1CN(CC2=CC=C(F)C=C2)CCO1
Smiles: CC1C=CC(=CC=1)S(=O)(=O)N1CCCC[C@@H]1C(=O)NC1=NC(=CS1)C1C=CC(=CC=1)OC
Michel Weïwer
Teniposide - CAS# 29767-20-2 Catalog No.:M9752-10 98(6):630-8Teniposide is a semisynthetic derivative of podophyllotoxin with antineoplastic activity. Teniposide forms a ternary complex with the enzyme topoisomerase II and DNA, resulting in dose dependent single and double stranded breaks in DNA, DNA: protein cross links, inhibition of DNA strand religation, and cytotoxicity. This agent acts in the late S or early G phase of the cell cycle. Product information CAS Number: 29767 20 2 Molecular Weight: 656. 65