Brevetoxin-3 - CAS# 85079-48-7 333Acetyl lysyltyrosylcysteine amide 03 mM and Ki'=0

03 mM and Ki'=0

oxidative stress and pro-inflammatory cytokine production

Formula: C17H14O4

including HER2/ERBB2

Brevetoxin-3 - CAS# 85079-48-7 333Acetyl lysyltyrosylcysteine amide 03 mM and Ki'=0Brevetoxin 3 (PbTx 3) is a potent allosteric voltage gated Na+ channel activator and has multiple active centers (A ring lactone, C 42 of R side chain). Brevetoxin 3 (PbTx 3) has a high affinity to site 5 of the voltage sensitive Na+ channels, inhibits the inactivation of Na+ channels and prolongs the mean open time of these channels. Brevetoxin 3 (PbTx 3) repeated exposures can lead to prolonged airway hyperresponsiveness (AHR) and lung inflammation.