SP600125 345541 Development of Inhibitors of the

Development of Inhibitors of the PAS-B Domain of the HIF-2α Transcription Factor

UNC1215 binds to L3MBTL3 with a Kd of 120 nM (IC50 ~ 20 nM)

most significantly

MCT-14-0219

SP600125 345541 Development of Inhibitors of theSP 600125 is a specific JNK inhibitor. SP600125 kills p53 deficient cells more efficiently than their p53 proficient counterparts, in vitro. Similar observations were obtained in vivo, in mice carrying p53 deficient and proficient human xenografts. Product information CAS Number: 129 56 6 Molecular Weight: 220. 23 Formula: C14H8N2O Synonym: SP 600125 SP 600125 Chemical Name: dibenzo[cd, g]indazol 6(2H) one Smiles: O=C1C2=CC=CC=C2C2=NNC3=CC=CC1=C32