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Bioymifi was used at 5-10 µM final concentration in vitro and in cellular assays
Srivastava M
Currently CI994 is in phase III clinical trials for lung cancer
Solubility: DMSO up to 25 mM
Nocodazole - Microtubule Inhibitor / CRISPR Editing Enhancer. CAS# 31430-18-9 60239 Bioymifi was used at 5-10Nocodazole, CAS No. 31430 18 9, is a potent microtubule inhibitor to inhibit mitosis. It disrupts microtubules by binding to tubulin and preventing formation of one of the two interchain disulfide linkages, thus inhibiting microtubule dynamics, disruption of mitotic spindle function, and fragmentation of the Golgi complex. Nocodazole arrests the cell cycle at G2 M phase and also prevents phosphorylation of the T cell antigen receptor and inhibits its
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