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CGS 19755 Catalog No.:M23351-C P-glycoprotein (ABCB1/MDR1) limits brain accumulation

SKU: 13898199518

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Description

P-glycoprotein (ABCB1/MDR1) limits brain accumulation and Cytochrome P450-3A (CYP3A) restricts oral availability of the novel FGFR4 inhibitor fisogatinib (BLU-554)

OC1(CN2C=CC=CC2=O)CCN(CC2C=CC=CC=2)CC1

3)22-8-6-18(14-23(22)30)32-27(16-4-9-24-25(12-16)37-11-10-36-24)20(15-26(33)34)19-7-5-17(31)13-21(19)28(32)35/h4-9

It has been shown to produce sedative and anorectic effects in animals

CGS 19755 Catalog No.:M23351-C P-glycoprotein (ABCB1/MDR1) limits brain accumulationProduct information CAS Number: 110347 85 8 Molecular Weight: 223. 16 Formula: C7H14NO5P Chemical Name: (2S,4R) 4 (phosphonomethyl)piperidine 2 carboxylic acid Smiles: OC(=O)[C@@H]1C[C@H](CP(O)(O)=O)CCN1 InChiKey: LPMRCCNDNGONCD RITPCOANSA N InChi: InChI=1S C7H14NO5P c9 7(10)6 3 5(1 2 8 6)4 14(11,12)13 h5 6,8H,1 4H2,(H,9,10)(H2,11,12,13) t5 ,6+ m1 s1 Technical Data Appearance: Solid Power Purity: 98% (or refer to the Certificate of Analysis) Shipping

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