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MDV-3100 has greater affinity to AR than ICI 176334 does in a competition assay with 16β-[18F]fluoro-5α-DHT (18-FDHT) in castration-resistant LNCaP/AR cells (AR-overexpressing)
and inhibits wet-dog shakes (WDS)-like cold hypersensitivity in mice by 63% at 30 mg/kg
CAS Number: 1259389-38-2
These factors have led the U
Butaprost Catalog No.:M11759-2 MDV-3100 has greater affinity toButaprost is a selective prostaglandin E receptor (EP2) agonist with an EC50 of 33 nM and a Ki of 2. 4 M for murine EP2 receptor. Butaprost is less activity against murine EP1, EP3 and EP4 receptors. Butaprost attenuates fibrosis by hampering TGF Smad2 signalling. Product information CAS Number: 69685 22 9 Molecular Weight: 408. 57 Formula: C24H40O5 Chemical Name: methyl 7 [(1R, 2R, 3R) 3 hydroxy 2 [(1E, 4S) 4 hydroxy 4 (1 propylcyclobutyl)but 1 en 1
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