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GNF-2 accelerated osteoclast apoptosis by inducing caspase-3 and Bim expression
LY 2109761
1009820-21-6
Formula: C18H25N5S2
CK-1827452 - CAS# 873697-71-3 228 GNF-2 accelerated osteoclast apoptosis byCK 1827452, CAS No. 873697 71 3, is a cardiac specific myosin activator. It is clinically tested for its role in the treatment of left ventricular systolic heart failure. CK 1827452 specifically targets and activates myocardial ATPase and improves energy utilization. CK 1827452 improves systolic function by increasing the systolic ejection duration stroke volume, without consuming more ATP energy, oxygen or altering intracellular calcium levels
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