Capromorelin Tartrate 60107 TAMR-1 and 182R-6[1]

TAMR-1 and 182R-6[1]

7(12):1597-616

and represses tumor growth

Treatment of microglial BV2 cells with 10 μM AGK2 also leads to a significant decrease in the intracellular ATP and significant increases in both late-stage apoptosis and necrosis of the cells

Capromorelin Tartrate 60107 TAMR-1 and 182R-6[1]Capromorelin Tartrate, also known as CP 424, 391, is a growth hormone secretagogue and ghrelin mimetic ( hGHS R1a K(i)=7 nM, rat pituicyte EC(50)=3 nM). Initial studies have shown the drug to directly raise insulin growth factor 1 (IGF 1) and growth hormone levels. Capromorelin showed enhanced intestinal absorption in rodent models and exhibited superior pharmacokinetic properties, including high bioavailabilities in two animal species [F(rat)=65%,