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24 hours) induces upregulation of cell cycle inhibitors
This prevents both the activation of the B-cell antigen receptor (BCR) signaling pathway and BTK-mediated activation of downstream survival pathways
Barasertib is a prodrug and will be converted rapidly to the active drug AZD1152-HQPA in human plasma
SF1126 (0-6 µM
23-Hydroxybetulinic acid Size:Contact [email protected] for quotation 24 hours) induces upregulation of23 hydroxybetulinic acid is one of the bioactive components responsible for its anticancer activity. In vitro: 23 hydroxybetulinic acid also shows different proliferation inhibitory activity against B16, HeLa, and HUVEC, with the IC50 value of 78. 5, 80, and 94. 8 uM, respectively. 23 hydroxybetulinic acid can promote cell cycle arrest at S phase and induce apoptosis via intrinsic pathway. 23 hydroxybetulinic acid disrupts mitochondrial membrane
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