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1092351-67-1
23(3):274-6
It has no activity at other histone methyltransferases
CAS Number: 55368-40-6
MC1568 - Class IIa HDAC Inhibitor. CAS# 852475-26-4 0318 1092351-67-1MC1568, CAS No. 852475 26 4, is a potent and selective inhibitor of class IIa histone deacetylases (HDACs), with IC50 of 100 nM for maize HD1 A. It is 34 fold more selective for HD1 A than HD1 B, 176 fold more selective for class I HDACs. It exhibits tissue selective inhibition between members of class II deacetylases in vivo; inhibits HDAC4 and HDAC5 in skeletal muscle and the heart without affecting HDAC3 activity. It arrests myogenesis through the
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