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InChiKey: INBGSXNNRGWLJU-ZHHJOTBYSA-N
or CH5424802 or RO5424802
Hu7691 free base has a significant inhibitory effect on the growth of 18 kinds of human tumor cells (U87-MG
InChiKey: CYOVYGWNDHLPBF-UHFFFAOYSA-N
APG-1387 l D6 Nitrate InChiKey: INBGSXNNRGWLJU-ZHHJOTBYSA-NAPG 1387, a bivalent SMAC mimetic and an IAP antagonist, blocks the activity of IAPs family proteins (XIAP, cIAP 1, cIAP 2, and ML IAP). APG 1387 induces degradation of cIAP 1 and XIAP proteins, as well as caspase 3 activation and PARP cleavage, which leads to apoptosis. APG 1387 can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal carcinoma. Product information CAS Number: 1570231 89 8 Molecular Weight: 1157.