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PF-2545920 - CAS# 898562-94-2 size:2mg solid The effect of KN62 on

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Description

The effect of KN62 on Ca(2+)-influx appears to be specific to slowly-or non-inactivating conductances

PF-2545920 - CAS# 898562-94-2 size:2mg solid The effect of KN62 onPF 2545920, also known as Mardepodect, CAS No. 898562 94 2, is a phosphodiesterase inhibitor selective for the PDE10A subtype, which is potentially useful for the treatment of schizophrenia. Phosphodiesterase 10A (PDE10A) is highly expressed in striatal medium spiny neurons of both the direct and indirect output pathways. PDE10A inhibitors have shown behavioral effects in rodent models that predict antipsychotic efficacy. PF 2545920 is active in a

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