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CAS Number: 869185-85-3
3-difluorocyclobutyl)-pyrazole derivatives as novel potent transforming growth factor-β type 1 receptor inhibitors
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KL1333 011381 CAS Number: 869185-85-3KL1333, a derivative of lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD(P)H: quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin induced ototoxicity in mouse cochlear cultures. Product information CAS Number: 1800405 30 4 Molecular Weight: