PF-3758309 hydrochloride Size:Contact [email protected] for quotation which increases the ratio of

which increases the ratio of relative protein expression of Bcl-xL and Bax in early periods

24 hours) induces MOLT-4 and Jurkat cells apoptosis

and the effect of KL201 is blunted by knockdown of FBXL3

Xuan Zhang

PF-3758309 hydrochloride Size:Contact [email protected] for quotation which increases the ratio ofPF 3758309 hydrochloride is a potent, orally available, and reversible ATP competitive inhibitor of PAK4 (Kd= 2. 7 nM; Ki=18. 7 nM). PF 3758309 hydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation. Product information CAS Number: 1279034 84 2 Molecular Weight: 527. 08 Formula: C25H31ClN8OS Chemical Name: (S) N