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GLL398 strongly binds to ERα in a fluorescence resonance energy transfer binding assay (IC50 =1
IC50 48h: 6
GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0
LIANA PLES
PIP4K-IN-a131 Catalog No.:M24097-C GLL398 strongly binds to ERαPIP4K IN a131 is PIP4K lipid kinases inhibitor, with IC50s of 1. 9 M and 0. 6 M for purified PIP4K2A and PIP4Ks, respectively. PIP4K IN a131 exhibits cancer selective lethality via dual blockade of the lipid kinase PIP4Ks and mitotic pathways. Product information CAS Number: 2055405 95 1 Molecular Weight: 295. 34 Formula: C20H13N3 Chemical Name: (2Z) 2 (1H indol 3 yl) 3 (isoquinolin 5 yl)prop 2 enenitrile Smiles: N#C C(=C\C1=CC=CC2=CN=CC=C12)
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