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PubMed PMID: 1914378
and anchorage-independent colony formation in soft agar
PMID: 33012874
The mean IC50 value of 47 nM for Narciclasine across a panel of 60 cancer cell lines[1]
K-252a - CAS# 99533-80-9 60261 PubMed PMID: 1914378K 252a, CAS No. 99533 80 9, also known as SF 2370, is an alkaloid isolated from Nocardiopisis bacteria. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1. 8 and 1. 7 nmol L, respectively). At higher concentrations it is also an efficient inhibitor of serine threonine protein kinases (IC50 of 10 to 30 nmol L). Product information CAS Number: 99533 80 9 Molecular Weight: 467. 47