Silibinin xin Hydrochloride SAR407899 is a potent and

SAR407899 is a potent and ATP-competitive ROCK inhibitor

4-Dihydroxystyryl)-4-hydroxy-2-pyrone

CPI-169 shows a dose-dependent inhibitory effect on cell viability

followed by HE staining

Silibinin xin Hydrochloride SAR407899 is a potent andSilibinin, CAS#22888 70 6, also known as silybin, contains both A and B diastereomers. Silibinin is the major active constituent of silymarin, standardized extract of the milk thistle seeds, containing mixture of flavonolignans consisting of among others of silibinin, isosilibinin, silicristin and silidianin. Silibinin itself is mixture of two diastereomers Silibinin A and Silybinin B in approximately equimolar ratio. Both in vitro and animal research